Dear authors,
The topic of your manuscript has been evaluated as of great scientific interest and the overall presentation of high quality. I am, therefore, pleased to accept your manuscript for publication with the minor modifications presented in your answer to the reviewers.
I have just a few additional minor comments (see below) that you might want to address.
Sincerely,
Christine Klaas

Figure 1: why is the timeline in the left panel (difficult to read but simulation time goes up to 1400 year?) longer than for the other two panels.

p.5 line 26: What is meant by "stratification starts to reduce"? If it refers to the RU simulation, shouldn't stratification actually increase?

p.11, lines 14-15: Why would cell size and calcification increase with increasing temperatures? Laboratory studies shows mostly a decrease in calcification. It seems that the authors refer to changes in an evolutionary scale (rise of new species) which would not apply to the time-scale of the simulations presented here.

Figure A1: please specify that the data presented correspond to the transient response of RD and RU runs in NPP and RESP and temperature. In particular, I assume that the temperatures shown correspond to the response of global ocean average temperature from start to end of each simulation?